ISSN: 2329-8790
+44 1478 350008
Woodland Avenue Practice, Luton, UK
Dr. Joseph is an eminent researcher. Currently he is working at Woodland Avenue Practice, Luton, UK. He has many publications. His area of expertise is Non-vitamin K oral anticoagulation, Arrhythmia; Renal function, Tachycardia .
Original Research Article
Accuracy of NOAC Prescribing in Primary and Secondary Care: Retrospective Cohort Study
Author(s): Joseph R Smith* and Manraj Barhey
This retrospective multi-centred cohort study assessed non-vitamin K oral anticoagulation (NOAC) prescribing in
4 separate general practices in the UK. Using NICE clinical knowledge skills (NICE-CKS) guidelines we assessed
the accuracy and validity of NOAC prescribing. We identified 337 patients on NOACs. The most commonly
prescribed NOAC was Apixaban (65.3%), followed by Rivaroxaban (20.5%), Dabigatran (10.4%) and Edoxaban
(3.8%). Prescribing was predominantly carried out in secondary care (wards 51.9%, clinics 19.3%) with 28.8% of
prescribing in general practice. The most common indication requiring anticoagulation was arrhythmias (80.1%),
followed by venous thrombus embolus (VTE) (18.1%). The remaining indications were for unlicensed use (1.8%)
including left ventricular thrombus, portal vein thrombus, and cardiac transplant. Furthermore, of the patients on
.. View More»