Journal of Clinical Toxicology
Open Access

Department for Antiviral Research, Utah State University, Logan, UT, USA

Biography

Dr. Justin Julander, Animal, Dairy and Veterinary Sciences Virology, Antiviral. Currently working at Institute for Antiviral Research, Utah State University, Logan, UT, USA. Research Interest : Antiviral Research.

Publications: Efficacy of the broad-spectrum antiviral compound BCX4430 against Zika virus in cell culture and in a mouse model.

 

Publications

• Research Article   
  In vitro Inactivation of SARS-Cov-2 by Povidone-Iodine In situ Gel Forming Solution
  Author(s): Bo Liang*, Xudong Yuan, Gang Wei, Wei Wang, Ming Zhang, Haizhou Peng, Juan C. Hernaiz-Leonardo, Amin Javer, Michelle Mendenhall, Justin Julander, Sammi Huang, Hany Michail, Yong Lu, Qi Zhu and John Baldwin
  
  Background: Povidone Iodine (PVP-I) nasal solutions are effective against the SARS-CoV-2 virus, but are cleared rapidly from the nasal cavity, limiting its use. PVP-I gel forming solutions can circumvent this problem due to their higher viscosity and prolonged clearing time. Objective: Characterize the in vitro virucidal activity of long-acting PVP-I compositions developed using an in situ gel forming technology against the SARS-CoV-2 virus and test its safety using a rat model. Methods: We tested different dilutions of the PVP-I gel forming solution– full concentration, 90%, 50%, 28% and 9% of the original formulation concentration – at varying exposure times to assess virucidal activity against SARSCoV- 2 in VERO76 cells infected. Virucidal activity was recorded as the reduction of v.. View More»
  DOI: 10.35248/2161-0495.21.s18.002

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