ISSN: 2472-4971
Divsion of Surgical Oncology and Endocrine Surgery, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
Dr. Kamran Idrees is Director of the Pancreas and GI Surgical Oncology and Director of the Peritoneal Surface Malignancy Program at Vanderbilt-Ingram Cancer Center. After completing his general surgery training at University of Alabama at Birmingham, he finished a clinical fellowship in Surgical Oncology at the University of Pittsburgh Medical Center, where he was trained in regional perfusion treatments including Heated Intra-Peritoneal Chemotherapy (HIPEC) and Isolated limb infusion (ILI).
Research
Peritoneal Carcinomatosis in Well-Differentiated Small-Intestinal Neuroendocrine Tumors with Mesenteric Tumor Deposits
Author(s): Satya Das*, Chanjuan Shi, Tatsuki Koyama, Yi Huang, Raul Gonzalez, Kamran Idrees, Christina Edwards Bailey and Jordan Berlin
Objective: Well-differentiated small-intestinal neuroendocrine tumors (SI-NETs) tend to be biologically indolent.Despite this tendency, they have a predilection for metastasis. Peritoneal involvement is quite common as isunfortunately peritoneal carcinomatosis (PC). PC is a dreaded metastatic complication due to the significant morbidity it creates for patients as well as well as increasing their mortality risk. The risk factors for PC development in SI-NETs remain understudied; however, one such factor may be the presence of mesenteric tumor deposits (MTDs).
Methods: We performed a retrospective analysis on 208 well-differentiated SI-NET patient samples, the majority with mesenteric masses, from the pathology archives of Vanderbilt University Medical Center. We sought to explore whether MTD presence was associated with PC, what other patien.. View More»