ISSN: 2157-7064
+44 1300 500008
Department of Analytical Chemistry, University of Melbourne, Melbourne, Australia
Dr. Katrina Nueva is a researcher in the Department of Analytical Chemistry at the University of Melbourne, Australia. Her work focuses on extracellular brain metabolomics, utilizing liquid chromatography techniques to analyze metabolites in the brain's extracellular space. In her recent publication, "Examining the Extracellular Brain Metabolomics through Liquid Chromatography," Dr. Nueva explores the principles, applications, and implications of extracellular brain metabolomics using liquid chromatography. LONGDOM In this study, Dr. Nueva discusses how liquid chromatography coupled with mass spectrometry (LC-MS) enables sensitive detection and identification of metabolites based on their mass-to-charge ratios. She emphasizes the importance of analyzing metabolites such as neurotransmitters, amino acids, and lipids, which play crucial roles in neuronal communication and energy metabolism. The research highlights the potential of LC-MS-based metabolomics studies to investigate neurotransmitter release dynamics, metabolic fluxes, and metabolic alterations associated with neurodegenerative diseases. LONGDOM Dr. Nueva's research contributes significantly to the field of analytical chemistry by advancing methodologies for analyzing complex extracellular metabolite mixtures in brain samples. Her work has implications for understanding brain function, disease mechanisms, and therapeutic interventions. By leveraging the sensitivity and selectivity of LC-MS, Dr. Nueva's research aims to elucidate metabolic pathways and advance our understanding of brain health and disease. LONGDOM
Perspective
Examining the Extracellular Brain Metabolomics through Liquid Chromatography
Author(s): Katrina Nueva*
DOI:
10.35248/2161-0940.24.15.550