ISSN: 2167-0870
Department of Cardiology, TMG Asaka Hospital, Saitama, Japan
Dr. Kazumiki Nomoto is currently working in Department of Cardiology, TMG Asaka Hospital, Saitama, Japan. He has published numerous research papers and articles in reputed journals and has various other achievements in the related studies. He has extended his valuable service towards the scientific community with his extensive research work.
Research Article
Design and Rational for a Prospective Randomized Study of Safety Outcomes Treated with Edoxaban in Patients with Stable Coronary Artery Disease and Atrial Fibrillation (PRAEDO AF Study)
Author(s): Daisuke Fukamachi, Yasuo Okumura*, Naoya Matsumoto, Eizo Tachibana, Koji Oiwa, Makoto Ichikawa, Kazumiki Nomoto, Hironori Haruta, Ken Arima and Atsushi Hirayama
Background: In non-valvular atrial fibrillation (NVAF) patients with coronary artery disease (CAD), using antiplatelet drugs in addition to anticoagulants for stroke prevention may further increase the bleeding risk. Several guidelines have recommended an oral anticoagulant (OAC) monotherapy in patients with stable CAD one year after percutaneous coronary intervention (PCI). When considering early neointima healing of current 3rd generation drug-eluting stents (DESs), the duration of the de-escalation from a single antiplatelet drug plus an OAC to an OAC alone therapy can be shortened by less than one year after PCI. The data on the clinical acceptability of short durations for de-escalation to an edoxaban monotherapy in those patients are still lacking. Methods: A multicenter, prospective, randomized, open-label, parallel group study has been established to investigate the safety out.. View More»
DOI:
10.35248/2167-0870.20.10.405