Journal of Nanomedicine & Biotherapeutic Discovery
Open Access
ISSN: 2155-983X
+44 1300 500008
ISSN: 2155-983X
+44 1300 500008
Department of Geriatric Medicine, Tokyo Medical University, Tokyo, Japan
Research Article
Brain Volume and White Matter Lesions Associated with Sarcopenia in Older Patients
Author(s): Tomohiko Sato*, Akito Tsugawa, Daisuke Hirose, Yusuk Ogawa, Yoshitsugu Kaneko, Naoto Takenoshita, Kentaro Hirao, Hidekazu Kanetaka, Haruo Hanyu and Soichiro Shimizu
Background: Sarcopenia reduces activities of daily living in older individuals and has been attracting attention as a cause of needing nursing care. A relationship between white matter damage and sarcopenia has been suggested, but the details remain unclear. Here, we investigated the relationship between brain volume and sarcopenia in older patients who visited an outpatient memory clinic.
Methods: A total of 218 older patients (Mean age: 80.3 ± 6.6 years) who visited our outpatient memory clinic completed the Mini-Mental State Examination and Geriatric Depression Scale-15. Height, weight, grip strength, muscle strength (measured by bioimpedance), and walking speed were determined. Sarcopenia was assessed using the Asian Working Group on Sarcopenia diagnostic criteria. From magnetic resonance images of the head, Total Brain Volume (TV.. View More»
DOI:
10.4172/2155-983X.24.14.251