Pharmaceutical Analytical Chemistry: Open Access
Open Access

Pharmaceutical Analytical Chemistry Department, Modern University for Technology and Information (MTI), Cairo University, Cairo, Egypt

Biography

Khadiga M. Kelani  was Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini St, ET- 11562, Cairo, Egyp. Khadiga M. Kelani is the Editorial Board Member of many peer reviewed journals and area of expertise, as an Research Scholar credits with many publications in national and international journals. Sophie Holowacz is committed to highest standards of excellence and it proves through his/her co-authorship of many books.

Publications

• Research Article   
  A Recent Validated Synchronous Spectrofluorimetric Method in Comparative to Ratio Derivative One for Determination of Desmopressin Acetate in Dosage Form and Biological Fluids
  Author(s): Khadiga M. Kelani, Ahmed M.Wafaa Nassar*, Wael Talaat and Samir Morshedy
  
  In this study green, rapid, specific and highly sensitive methods have been developed and validated for the determination of desmopressin acetate in pharmaceutical formulations and biological fluids (spiked human plasma). Second derivative synchronous spectrofluorimetric method Ratio derivative spectrophotometric method: Sensitivity ranges of (0.25–2.25 μg/ml) and (2–14 ug/ml) and LOD and LOQ values were found to be (0.060-0.183 ug/ml), (0.049-0.162 ug/ml), respectively. The developed methods were validated according to the (ICH) guidelines demonstrating good accuracies and precisions. The results of the developed methods were statistically compared with those obtained by the reported methods without any significant difference. Both methods were applied in quality control laboratories and in routine analysis for analyzed the drug in presence of its acidic degradation pr.. View More»
  DOI: 10.35248/2471-2698.21.6.138

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