ISSN: 2161-0940
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Research Article
Effect of Enriched Environment on the Cognitive and Behavioural Changes in the Streptozotocin-Induced Young Diabetic Rats
Author(s): Rajashree R*, Khlokute SD and Goudar SS
Introduction: Effects of juvenile diabetes on the central nervous system are less well documented. Effective management of T1DM is another major challenge as insulin is the only available effective treatment. Hence, easily available, affordable, non-invasive therapies like enriched environment are the need of time.
Objectives: The present study aimed to determine the effect of an enriched environment on cognitive and behavioral changes in juvenile diabetic rats.
Methods: Diabetes was induced in 25 days old, albino Wistar rats, by streptozotocin (STZ). Animals were reared in an enriched environment and treated with herbal formulae with Salacia R and Clitoria T. Then, rats were tested in the elevated passive maze, passive avoidance box and Morris water maze (n=6). Values are expressed as means ± SE and differe.. View More»
DOI:
10.35248/2161-0940.19.9.316