Journal of Clinical & Experimental Dermatology Research
Open Access

Dermatology Clinic, Ospedale Centrale di Bolzano (BZ), Bolzano, Italy

Publications

• Research Article   
  Efficacy of a Urea, Omental Lipids, Carnosine and Panthenol Cream in the Treatment of Severe Foot Xerosis in Diabetic Subjects: A Randomised, Controlled, Assessor-Blinded Prospective Trial
  Author(s): Mario Puviani, Klause Eisendle, Liboria Adamo and Massimo Milani*
  
  Background: Xerosis is a common skin manifestation in subjects with diabetes. Severe xerosis with or without fissuration of lower limbs and foot is a risk for the development of foot ulcer. Skin foot care in diabetics is a relevant strategy to prevent further skin damage. Topical urea and other emollient substances are commonly used to improve skin hydration and skin elasticity of lower limbs and feet. Pure Omental Lipids (POL) used topically has shown to improve skin mechanics and strength in fragile skin. Carnosine could interfere with the formation of advance glycated end-products which seem to be responsible of increased stiffness and reduced elasticity of the skin in diabetic subjects. Panthenol is a potent emollient with skin barrier functions defence activity. Recently a topical product containing urea, POL, carnosine and panthenol has been developed (POL-P)... View More»
  DOI: 10.35841/2329-9509.22.13.616

  Abstract HTML PDF