Journal of Clinical Toxicology
Open Access
ISSN: 2161-0495
+44 1478 350008
ISSN: 2161-0495
+44 1478 350008
Department of Pharmacy, Loma Linda University Children’s Hospital, Loma Linda, CA, USA
Dr. Komal A. Patel Department of Pharmacy, Loma Linda University Children’s Hospital, Loma Linda, CA, USA his publications are Baclofen Neurotoxicity in a Pediatric Patient on Peritoneal Dialysis
Case Report
Baclofen Neurotoxicity in a Pediatric Patient on Peritoneal Dialysis
Author(s): Cristina M. Farkas Skiles*, Michael D. Levine, Komal A. Patel and Rachana Srivastava
We describe a 2-year-old patient with End Stage Kidney Disease (ESKD) on Continuous Cycling Peritoneal Dialysis (CCPD), gastroesophageal reflux disease, gastric tube dependence who presented with hypotension, confusion and lethargy 1 day after initiating oral baclofen for chronic vomiting. Sepsis work up and baclofen level were sent, later showing baclofen level of 0.55 mcg/ml. The patient required norepinephrine and CCPD for 24 hours before returning to baseline. CCPD was continued for 33 hours and he was discharged home at baclofen level of 0.25 mcg/mL... View More»