Immunotherapy: Open Access
Open Access

Department of Urology, Shenzhen-Shanwei Central Hosopital, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Shanwei City, Guangdong Province, 516600, P.R. China

Publications

• Research Article   
  ncRNAs-mediated Upregulation of GTSE1 is Involved in the Poor Prognosis and Tumor Immune Infiltration of Clear Cell Renal Cell Carcinoma
  Author(s): Kuang Xiayu and LI Canxuan*
  
  Aims: Examine GTSE1 expression and function in renal clear cell carcinoma, as well as the nc-RNA that is upstream of GTSE1 . Methods: The Cancer Genome Atlas (TCGA) provided clinical and RNA-seq data for ccRCC patients, and the expression of GTSE1 , its connection with clinical data, prognosis and tumor immune infiltration, and prediction of upstream noncoding RNAs (nc-RNAs) of GESE1 were analyzed using R language and public tumor databases. Results: In ccRCC, GTSE1 is highly expressed and is linked to a high clinical stage and a poor prognosis. In ccRCC, the PVT1/has-mir-23b-3p/ GTSE1 axis has been identified as the most likely upstream ncRNA related route of GTSE1 . Furthermore, GTSE1 expression was linked to tumor immune cell infiltration, .. View More»
  DOI: 10.35248/2471-9552.22.8.198

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