Advances in Pediatric Research
Open Access

Department of Pediatric Anesthesia and Critical Care, Necker Enfants Malades University Hospital, Assistance Publique Hôpitaux de Paris, APHP, University of Paris, Paris, France https://orcid.org/0000-0002-9748-5141, Ecole Doctorale 563 Médicament-Toxicologie- Chimie-Imageries (MTCI), Université de Paris, France

Publications

• Research   
  Goal directed fluid and hemodynamic therapy and postoperative outcomes in children: Value of trans-thoracic echocardiographic aortic blood flow peak velocity variation: A multi centre randomized controlled trial protocol
  Author(s): Kumba Claudine*
  
  Background: While several parameters of fluid responsiveness have been validated in adults, they cannot be directly applied in children primarily because of the pediatric specificities of the cardiovascular system. Respiratory variation of Aortic Blood Flow Peak Velocity (ΔVpeak) has been promoted as an accurate predictor of fluid responsiveness in children. Therefore, we aim at characterizing the potential impact of optimization of intraoperative hemodynamic condition using goal directed fluid and hemodynamic therapy (GDFHT based on ΔVpeak assessed by transthoracic echocardiography on postoperative outcome in children. Methods: Children aged less than 18 years old and admitted for major non cardiac surgery will be eligible. After obtaining parental consent, children will be randomized into two groups: Group GD, where fluid and h.. View More»
  DOI: 10.35248/2385-4529.21.8.57

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