ISSN: 2385-4529
Department of Pediatric Anesthesia and Critical Care, Necker Enfants Malades University Hospital, Assistance Publique Hôpitaux de Paris, APHP, University of Paris, Paris, France https://orcid.org/0000-0002-9748-5141, Ecole Doctorale 563 Médicament-Toxicologie- Chimie-Imageries (MTCI), Université de Paris, France
He is affiliated to Department of Pediatric Anesthesia and Critical Care, Necker Enfants Malades University Hospital, Assistance Publique Hôpitaux de Université de Paris, France He is a recipient of many awards and grants for his valuable contributions and discoveries in major area of subject research. His international experience includes various programs, contributions and participation in different countries for diverse fields of study. His research interests reflect in his wide range of publications in various national and international journals.
Research
Goal directed fluid and hemodynamic therapy and postoperative outcomes in children: Value of trans-thoracic echocardiographic aortic blood flow peak velocity variation: A multi centre randomized controlled trial protocol
Author(s): Kumba Claudine*
Background: While several parameters of fluid responsiveness have been validated in adults, they cannot be directly applied in children primarily because of the pediatric specificities of the cardiovascular system. Respiratory variation of Aortic Blood Flow Peak Velocity (ΔVpeak) has been promoted as an accurate predictor of fluid responsiveness in children. Therefore, we aim at characterizing the potential impact of optimization of intraoperative hemodynamic condition using goal directed fluid and hemodynamic therapy (GDFHT based on ΔVpeak assessed by transthoracic echocardiography on postoperative outcome in children.
Methods: Children aged less than 18 years old and admitted for major non cardiac surgery will be eligible. After obtaining parental consent, children will be randomized into two groups: Group GD, where fluid and h.. View More»
DOI:
10.35248/2385-4529.21.8.57