ISSN: 2161-1017
+44 1478 350008
Department of Medicine, University of New Mexico, Albuquerque, USA
Case Report
Central Diabetes Insipidus Alternating with Cerebral Salt Wasting Syndrome in an Infant with an Acute Myeloid Leukemia
Author(s): Kyree Sky and Senan Hadid*
Central diabetes insipidus has been described as a rare complication of acute myeloid leukemia in adult patients.
This case report details a case of a 6 month old infant newly diagnosed with AML that was complicated by central
diabetes insipidus and concurrent cerebral salt wasting syndrome. As far as we know this is one of the first cases of
concurrent central diabetes insipidus and cerebral salt wasting syndrome in the setting of AML in a pediatric patient.
Our case documented a fluctuation between DI and CSW in a newborn with freshly diagnosed AML, necessitating
intensive monitoring of her serum Na and osmolality, urine output, Na and osmolality. Using vasopressin was
difficult owing to the frequent fluctuations in the given levels within 24 hours. Importantly, her brain MRI findings
in this case were normal. A similar instance was described in adults, but with.. View More»
DOI:
10.35248/2161-1017.23.12.372