Clinical Pediatrics: Open Access
Open Access
ISSN: 2572-0775
ISSN: 2572-0775
Department of Pediatrics, Chulalongkorn University, Bangkok, Thailand
Research Article
Time to Vasoactive Agents Initiation, Restricted Volume Resuscitation Effect on Fluid Balance and Clinical Outcomes in Children with Septic Shock
Author(s): Siripen Sanguanngam, Lalida Kongkiattikul and Rujipat Samransamruajkit*
Background: Several studies have shown that positive fluid balance is associated with worse outcomes in pediatric severe sepsis and septic shock patients. Early vasopressor administration in children with septic shock after ≤ 40 cc/kg of fluid bolus may be beneficial.
Methods: This is a retrospective analytic study in children with septic shock (aged between one month and 18 years from 2012-2020.) They were recruited at a referral tertiary university hospital in Bangkok, Thailand and were treated with either restricted volume resuscitation (≤ 40 cc/kg of fluid bolus) combined with vasopressors or standard volume resuscitation. The clinical effect on fluid balance and other outcomes were measured.
Results: One hundred and forty three patients were diagnosed with septic shock. Ninety three patients started vaso.. View More»
DOI:
10.35248/2572-0775.23.8.244