ISSN: 2736-6588
Department of Medical Laboratory Sciences, Universitatsklinikum Regensburg, Regensburg, Germany
He is currently working as head of department to Lars S Maier's Lab, University Hospital Regensburg, Germany. Department of Cardiology and Pneumonology, Universitätsmedizin Göttingen, Germany (2003-2014). Department ofd Physiology, Loyola University Chicago, USA ( 2001-2002). His research work include:Argatroban versus heparin in patients without heparin-induced thrombocytopenia during venovenous extracorporeal membrane oxygenation: a propensity-score matched study, Echocardiographic Evaluation of LV Function in Patients with Tachyarrhythmia and Reduced Left Ventricular Function in Response to Rhythm Restoration, etc.
Research Article
Evaluation of a Multimarker Panel in Chronic Heart Failure: A 10 Years Follow-Up
Author(s): Susanne Bauer*, Christina Strack, Ute Hubauer, Ekrem Ücer, Stefan Wallner, Andreas Luchner, Lars Maier and Carsten Jungbauer
Background: Chronic heart failure is a complex disease associated with various pathophysiological and biochemical
disorders. We assessed the 10 years prognostic role of a multimarker panel of markers for myocyte stress (GDF-15),
extra-cellular matrix remodeling (Galectin-3, mimecan, TIMP-1), inflammation (Galectin-3), myocyte injury (hs-TnT)
and angiogenesis (endostatin, IBP-4, IGF-BP-7, sFlt-1 and PLGF) head-to-head with the biochemical gold-standard
NT-proBNP.
Methods: Blood samplesfrom 149 patients with heart failure were analysed. After 10 years of follow-up (median
follow-up 104 months, IQR 43-117), data regarding rehospitalisation for chronic heart failure and all-cause-mortality
were acquired.
Results: Regarding Kaplan Meier analysis, all markers, dichotomized according to you denindex,.. View More»