Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Department of Dermatology, Centro de la Piel CEPI, Quito, Ecuador
Case Report
Epidermolysis Bullosa Acquisita: A Case Report
Author(s): Lafuente Cevallos Lizeth Verónica*, Ureña López Valeria Alexandra, Lascano Gallegos Nathalie and Palacios Alvarez Santiago Alberto
Epidermolysis Bullosa Acquisita (EBA) is a chronic autoimmune subepidermal blistering disease developed after
damage to type VII collagen by autoantibodies. Type VII collagen is the major component of anchoring fibrils in
the sub-lamina densa hemidesmosomes of the skin and squamous mucosas. The worldwide incidence is estimated
between 0.2-0.5/million inhabitants per year. Two major clinical variants have been described: the mechanobullous,
and the inflammatory EBA... View More»
DOI:
10.35248/2155-9554.11.s7.546