ISSN: 2155-9600
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Department of Radiation Oncology, The Fifth Medical Center of Chinese PLA General Hospital, China
Research Article
Effects of Nutritional Status on Peripheral Immune Cells in Patients with Nonsmall
Cell Lung Cancer
Author(s): Fang He, Dongliang Yang, Xiankui Zha, Ping Wang and Liang Xuan*
Background: The nutritional status affects gene expression in peripheral T lymphocytes; nevertheless, the link
between nutritional status and immunity of cancer patients is unclear. The aim of the research was to evaluate the
connection with nutritional parameters and the frequencies of T cells subsets on peripheral blood in non-small cell
lung cancer (NSCLC) patients.
Methods: We enrolled 170 NSCLC patients and 53 healthy volunteers who were age and gender matched. The
frequencies of circulating CD3+, CD4+, CD8+, naïve CD4+, memory CD4+, naïve CD8+, memory CD8+, and
regulatory T lymphocytes were assessed by the way of flow cytometry. Nutritional parameters including albumin,
globulin, albumin to globulin ratio (AGR), total protein (TP), pre-albumin (PA), body mass index (BMI), and
prognostic nutritional index (P.. View More»
DOI:
10.35248/2155-9600.22.12.1000856