Journal of Depression and Anxiety
Open Access

Wenzhou Medical University, Wenzhou, P.R. China

Publications

• Research   
  Late Positive Potential in Bipolar Disorder Reflecting Emotional Disorder: An Event-Related Potential Study
  Author(s): Qiang Zhou*, Li Jun Zhang, Liang Ying and Jia Chen
  
  Introduction: Bipolar disorder (BD) is an emotional disorder characterized by emotional instability. This study aims to investigate whether emotional disorders affect the cortical processing that regulates emotional stimuli. Methods: This study uses a passive viewing paradigm to compare event-related potentials (ERPs) of 21 subjects with bipolar disorder (BD), 25 subjects with schizophrenia (SZ), and 25 normal subjects (HC). Results: In the frontal and parietal areas (1) the late positive potential (LPP) amplitude of BD was greater than that of SZ and HC, and there was no difference in terms of peak latency. (2) In the occipital area, the amplitude and latency of P300 of SZ and BD were significantly larger than HC, but there was no difference between SZ and BD. (3) The behavioral results demonstrated that BDs’ va.. View More»
  DOI: 10.35248/2167-1044.19.8.339

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