ISSN: 2155-9554
+44 1478 350008
Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy
Mini Review
Use of Photodynamic Therapy for a Rare Inflammatory Skin Disease: Extragenital Lichen Sclerosus
Author(s): Luigi Coronella, Lorenzo Scaramuzzino, Nello Tommasino and Giuseppe Lauletta*
Extragenital Lichen Sclerosus (LS) poses diagnostic and therapeutic challenges due to its rarity and varied presentations. This report presents a case of LS affecting the face, resistant to conventional therapies, successfully treated with topical 5-Aminolevulinic Acid (ALA)-Photodynamic Therapy (PDT). A literature review highlights the difficulty in diagnosing extragenital LS and discusses various treatment options, including corticosteroids, calcineurin inhibitors, surgery, and emerging therapies such as ALA-PDT and Janus Kinase inhibitors (JAKi). ALA-PDT emerges as a promising alternative for refractory cases, offering efficacy and safety, while JAKi presents a novel option for longterm management... View More»
DOI:
10.35841/2329-9509.24.15.664