ISSN: 2167-0951
+44-77-2385-9429
Department of Dermatology, Gabba Dermatology, Queensland, Australia
Case Report
Successful Treatment of Refractory Folliculitis Decalvans with Adalimumab
Author(s): Clare Mahon* and Lynda Spelman
Folliculitis decalvans is a rare, chronic cicatricial alopecia. The hair loss and scarring associated with this condition
has a significant impact on quality of life, and can cause significant emotional distress. It arises in adults and presents
as an expanding patch of scarring alopecia on the scalp, with pustules, crusts, hair tufts and perifollicular
hyperkeratosis. Without treatment, this can lead to irreversible progressive hair loss, an increased risk of squamous
cell carcinoma development, and has severe psychosocial sequelae for patients. Treatment is difficult for this
condition, with many cases where patients are refractory to topical therapies and oral antibiotics or isotretinoin.
There is emerging literature on the use of TNF-α inhibitors for this condition due to the role of TNF in the cellmediated
response. Here, we .. View More»
DOI:
10.35248/2167-0951.23.13.210