ISSN: 2155-6148
Department of Pharmacy Practice, National College of Pharmacy, Kozhikode, Kerala, India
M K Unnikrishnan is an Department of Pharmacy Practice, National College of Pharmacy, Kozhikode, Kerala. His study interests major on emerging or re-emerging disease and the microbes- host interaction. In recent years, he has studied several viruses including HIV-1, human or avian influenza , dengue and Zika viruses. Currently , Dr. M K Unnikrishnan is the author/editors/reviewer in several international journals. He published 10 articles in many journals and the articles are informative and got good citations.
Research Article
Postoperative Pain Management in Lower Limb Surgery Patients using Transdermal Buprenorphine and Diclofenac Formulation
Author(s): Jobin John*, Reshma Avicot Renny, Chrismol Devassy, M K Unnikrishnan and Vijish Venugopal
Background: The present study was carried out to determine the difference in the effectiveness of buprenorphine
and diclofenac transdermal patches in attenuating postoperative pain, following lower limb orthopedic surgeries in a
tertiary care teaching hospital in Kerala, South India.
Methods: 88 patients who underwent lower limb orthopedic surgeries under spinal anesthesia were included in this
simple randomized single-blind study. Group A received transdermal Buprenorphine 10 mcg/h patch and Group B
received transdermal Diclofenac 200 mg patch. Both patches were, applied 30 minutes before spinal anesthesia and
the intensity of pain was determined using, Visual Analog Scale (VAS) and Faces Pain Scale (FPS-R). The pain scores
at every 4th hour for 24 hours were measured and recorded for all patients. Side-effects .. View More»
DOI:
10.35248/2155-6148.20.11.977