Advances in Pediatric Research
Open Access
ISSN: 2385-4529
+44 1223 790975
ISSN: 2385-4529
+44 1223 790975
College of Medicine, University of Alfaisal, Riyadh, Saudi Arabia
Research Article
Corticosteroid Sparing Agents in Frequent Relapsing and Steroid Dependent Nephrotic Syndrome in Children: A Single Center Retrospective Study
Author(s): Bashair Alabbasi*, Naif Abdulmajeed, Abdulmonem Alghamdi, Saeed Alzahrani, Saeed Alghwery and Majed Aloufi
Background: Children with Frequently Relapsing Nephrotic Syndrome (FRNS) or Steroid-Dependent Nephrotic Syndrome (SDNS) may be prescribed non-corticosteroid immunosuppressive agents whenever there is a failure to maintain remission with low-dose alternate-day prednisone and/or significant adverse effects of prednisone develop. A wide variety of immunosuppressive agents have been used in these patients to reduce the number of relapses and maintain remission.
Objectives: To evaluate the outcome of steroid sparing agents in the management of FRNS and SDNS in children with nephrotic syndrome.
Patients and methods: A retrospective study was conducted on all Steroid-Sensitive Nephrotic Syndrome (SSNS) children (1-11 years) who received any type of second line agents (e.g. CNI, MMF, cyclophosphamide, and Ritu.. View More»
DOI:
10.35248/2385-4529.22.9.049