Journal of Antivirals & Antiretrovirals
Open Access
ISSN: 1948-5964
+44 1300 500008
ISSN: 1948-5964
+44 1300 500008
Marketing Department, M/s Whirlwind Corporation, Mumbai, India
Review Article
Role of Pulmonary Surfactant in Gas Exchange Mechanism and Providing Protection against Progression of any Respiratory Viral Disease like SARS-CoV-2 and Need to focus it as First Point of Medication for all Respiratory Diseases
Author(s): Makarand Anand Phadke*
During inhalation oxygen molecules are drawn towards type I cells. The partial pressure difference and solubility
factor act as a Drive for this movement of oxygen molecules. It is well known that the pulmonary surfactant plays
an important role in gas exchange. The surfactant is thin mono-layer. The top surface of surfactant with SP-B and C
proteins faces alveolar air and is hydrophobic in nature and acts as a surface tension reducer, whereas lower surface
with SP-A and D proteins is hydrophilic and is adsorbed on mucosal layer. This lower surface of surfactant acts as
an anti-invader, pathogen barrier. However there is a small missing link in explaining its exact mechanism or role in
justifying these properties during normal conditions and during ‘viral ligand’ attack.
Similarly a unique physical property of SP-C component is listed in research .. View More»
DOI:
10.35248/1948-5964.21.s22.005