Journal of Hepatology and Gastrointestinal disorders
Open Access

Institute of Pharmacology, Madras Medical College and Hospital, Chennai, Tamil Nadu, India

Biography

Malathi K has authored of many research articles/books related to Hepatology and Gastroenterology. She is currently working as a Professor in the Department of Gastroenterology. Her research interests includes Hepatic and Gastric complications. She has successfully completed his Administrative responsibilities.

Publications

• Research Article   
  A Randomized Open Label Study to Evaluate the Efficacy and Tolerability of Synbiotic in the Treatment of Ulcerative Colitis
  Author(s): Malathi K, Nandini R, Dhanasekar KR and Shilpa BN*
  
  Introduction: Ulcerative Colitis (UC) is a chronic inflammatory condition of the colon affecting 5 million patients globally. Despite the recent clinical advances in drug therapies, patients continue to have exacerbations of UC. Alterations in gut microbiota, more specifically reduced intestinal microbial diversity, have been found to be associated with relapse of UC. Therefore therapeutic strategy targeting the gut microbiota has the potential to induce remission in UC. This study was done to evaluate the efficacy and tolerability of synbiotic as an adjuvant to standard therapy in patients with UC and to evaluate the ability of synbiotic in preventing relapse and prolonging the remission of UC. Methods: An interventional open label, randomized, comparative clinical trial was done with 32 patients. Patients were randomized into two groups, Stud.. View More»
  

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