Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Medical Department, Cantabria Labs Difa Cooper, Caronno P, Italy
Research Article
A Serum Containing Deschampsia antartica Extract, Ferulic Acid and Vitamin C has Anti-Pollutant Effects on Skin Exposed to High Tropospheric Ozone Levels: A Controlled Single-Blind, Prospective Clinical Trial in Women Living in Urbanized, Hi
Author(s): Massimo Milani*, Marco Piacentini and Leonardo Celleno
Introduction: Air pollution induces skin damage and accelerating skin aging processes, mainly through oxidative stress. Pollutant substances, such as particulate matter (PM10, PM2.5) and tropospheric ozone (O3), can activate specific intracellular receptors called AhR (Aryl-Hydrocarbon Receptors) and this activation is involved in the skin aging process. Deschampsia antartica aqueous extract (DAE) has shown, in vitro, to reduce the pollutant-induced AhR activation. Ferulic acid (FA) and vitamin C (VC) are well known potent anti-oxidant substances. A dermatological product in serum formulation containing DAE/FA/VC has been recently commercialized. This product has demonstrated in vivo to protect skin from pollution damage during winter season when PM10 levels are very high. No data have been published so far regarding the protective effect of this serum durin.. View More»