ISSN: 2167-0250
+44 1300 500008
Department of School of Medicine, University of Dundee, Scotland
Research Article
A Systematic Review Focusing on the Use of Slo1 and Slo3 as Potential Targets for the Modulation of Sperm Motility and the Development of a Male Contraceptive Pill
Author(s): Maria Eleni Dionelli*
Background: There is limited knowledge and research regarding male contraceptives. Surveys conducted by
pharmaceutical companies have shown that males will not take a pill that will affect their hormones. However,
data from a government survey conducted in the United Kingdom in 2019 showed that 33% of sexually active
men agreed on taking a male contraceptive pill, which is the exact same percentage of women that currently use a
hormonal contraception. This research project seeks to establish whether the stated evidence regarding Slo1 and
Slo3 as potential targets is adequate, whether there is evidence of the expression of Slo1 and/or Slo3 cellular
localization in human spermatozoa and whether it can lead to the development of a male contraceptive pill.
Methods: A systematic review on numerous databases was conducted. The sea.. View More»
DOI:
10.35248/2167-0250.21.10.233