Journal of Biomedical Engineering and Medical Devices
Open Access

Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, NY, USA

Biography

Dr. Maria Hancu is Currently Working at The Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, NY, Located in USA. Current Research Interest Includes Validation of a Novel Noxious Pressure Device for Use in fMRI Pain Studies.

Publications

• Research   
  Validation of a Novel Noxious Pressure Device for Use in fMRI Pain Studies
  Author(s): Marisa DiMarzio, Michael Spinrad, Maria Hancu, Ellinor Grinde, Jamie Chang, Julia Slyer, Michael Gillogly, Julia Prusik, Julie G. Pilitsis*, Eric Fiveland and Ileana Hancu
  
  Background: Most fMRI studies on pain perception utilized thermal stimuli due to the lack of a non-metallic reliable, reproducible mechanical stimulus. We explored 2 potential MR compatible mechanical devices and validated one that induced changes on fMRI. Purpose: To validate a noxious mechanical stimulus MR compatible device in a healthy cohort and a chronic pain cohort. Further to ensure this device caused changes on fMRI compared to a pressure device. Methods: Two-healthy controls underwent fMRI scans in the presence/absence of mechanical noxious stimuli using different devices. A paradigm for administering the stimuli with the most robust responses on fMRI was developed. Reproducibility of the device was confirmed in 10 chronic pain patients and age/gender-matched healthy controls. Comparisons of patient demog.. View More»
  DOI: 10.35248/2475-7586.19.4.138

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