ISSN: 2167-0412
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Department of Biotechnology, Azyme Biosciences Private Limited, Bengaluru, Karnataka, India
Research Article
Chemical Constituents Isolated from the Leaf Extracts of Amomum aculeatum Roxb. (Zingiberaceae), In Vitro Evaluation of their Antioxidant, Antimicrobial and Anti-inflammatory Activities
Author(s): Veerapura Narayanappa Yoganandamurthy, Ramanath Shubharani, Mariswamy Mahesh and Veerapura Narayanappa Murulidhara*
Members of the genus Amomum are well known for their biological activities. In the present study, chemical constituents, antioxidant, antimicrobial and anti-inflammatory activities with total phenols and total flavonoids from the leaf extract of Amomum aculeatum, belongs to the family Zingiberaceae were analysed. Chemical constituents screening was carried out following the standard protocols. Antibacterial activity was assayed by a well diffusion method using Muller Hilton agar media. Antifungal activity was analyzed by a well diffusion method using potato dextrose agar. Radical scavenging activity was evaluated by ABTS, DPPH and reducing power assay. Total phenols and flavonoids were estimated by waters 510 HPLC. The anti-inflammatory evaluation was conducted by inhibition of protein denaturation method. Chemical constituents screening showed the presence of tannin.. View More»