Journal of Probiotics & Health
Open Access

Department of Microbiology and Plant Pathology, University of Pretoria, Hatfield, South Africa

Publications

• Research Article   
  Encapsulation of Probiotics in Lipid-based Microparticles Using Supercritical Fluid Plasticization
  Author(s): Markus C. Labuschagne* and Mapitsi S. Thantsha
  
  A novel method for the encapsulation of probiotics has been developed using a supercritical carbon dioxide (scCO2)-based Particles from Gas Saturated Solutions (PGSS) process. The excipients used in microencapsulation using scCO2 are usually pharmaceutical-grade polymers that need Food and Drug Administration (FDA) approval. This study aimed to evaluate the suitability of two new food-grade materials with Generally Recognized as Safe (GRAS) status as candidate excipients for encapsulation of probiotic cultures. Compritol E 472 ATO and Vegetal BM 297 ATO were used to encapsulate Bifidobacterium lactis Bb12 using scCO2 as a plasticizer in the PGSS process. The resulting microparticles were characterized based on morphological properties, particle size distribution as well as encapsulation efficiency. Compritol E 472 ATO was found to b.. View More»
  DOI: 10.35248/2329-8901.22.10.281

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