ISSN: 2161-0495
+44 1478 350008
Department of Health Sciences, University of Arizona College of Medicine, Tucson, USA
Case Report
Rattlesnake Envenomation in the Setting of Disrupted Lymphatic Flow: A Case Series
Author(s): Molly Brady*, Mary Junak, Geoffrey Smelski and Farshad Mazda Shirazi
Objective: Rattlesnake envenomation is a pathophysiologically complex process with a range of local effects
including pain, erythema, local edema resembling compartment syndrome, ecchymosis that extends beyond the
bitten extremity, as well as the development of blisters, bullae and tissue necrosis in severe cases. Previous animal
studies have suggested that lymphatic flow is a crucial part of dissemination of venom after initial injection to
produce systemic effects. However, the effects of baseline lymphatic obstruction on local injury in humans have yet
to be described clinically.
Methods: Three cases of patients that sustained rattlesnake bites with a history of lymphatic disruptions were
reviewed, two with histories of mastectomies and one with chronic lower extremity lymphedema. All three patients
experienced bites on t.. View More»
DOI:
10.35248/2161-0495.20.10.455