Journal of Thyroid Disorders & Therapy
Open Access
ISSN: 2167-7948
+44 1300 500008
ISSN: 2167-7948
+44 1300 500008
Department of Clinical Laboratory Medicine, Hyogo Medical University School of Medicine, Nishinomiya, Japan
Dr. Masahiro Koshiba is a distinguished researcher affiliated with both the Department of Pharmacy Medicine at Avondale University in Cooranbong, Australia, and the Department of Clinical Laboratory Medicine at Hyogo Medical University School of Medicine in Nishinomiya, Japan. His research primarily focuses on immunology, endocrinology, and the development of novel therapeutic strategies for autoimmune diseases. Academic Background and Affiliations: Avondale University, Cooranbong, Australia: Dr. Koshiba is associated with the Department of Pharmacy Medicine, contributing to research and education in pharmaceutical sciences. Hyogo Medical University School of Medicine, Nishinomiya, Japan: He serves in the Department of Clinical Laboratory Medicine, engaging in research related to clinical diagnostics and laboratory medicine. Research Contributions: Dr. Koshiba has made significant contributions to the understanding of autoimmune diseases and thyroid disorders. Notable publications include: "Thyroid-Stimulating Antibody/Thyroid-Stimulating Hormone Receptor Antibody in Graves' Disease" Journal: Endocrine Practice Summary: This study investigates the role of thyroid-stimulating antibodies in Graves' disease, providing insights into autoimmune thyroid disorders. "Autoantibodies as Biomarkers in Thyroid Diseases" Journal: Journal of Thyroid Disorders & Therapy Summary: This review explores the potential of autoantibodies as diagnostic and prognostic biomarkers in various thyroid diseases. "Adenosine Inhibits TNFα-Induced MMP-3 Production in MH7A Rheumatoid Arthritis Synoviocytes via A2A Receptor Signaling" Journal: Scientific Reports Summary: This research examines the anti-inflammatory effects of adenosine in rheumatoid arthritis, highlighting its potential therapeutic applications.
Review
Autoantibodies as Biomarkers in Thyroid Diseases
Author(s): Masayoshi Nakano*, Ayako Miyazaki, Hiroe Konishi, Rika Yukimatsu, Toru Watanabe and Masahiro Koshiba
Thyroid diseases are common pathologies in primary care settings, and many patients with such diseases are treated by physicians who are not specialized in thyroid conditions. To diagnose such diseases earlier, some biological biomarkers have been identified. Anti-TSH receptor antibodies, which are considered the cause of Graves’ disease, are autoantibodies that bind to TSH receptors and activate the thyroid gland. The measurement of anti-TSH receptor antibodies is crucial for diagnosing, managing, and monitoring the treatment of Graves’ disease. This test has high sensitivity and specificity as a diagnostic tool. Conversely, antibodies against the TSH receptor do not have just one property; thus, the anti-TSH receptor antibody assay system could be improved to distinguish the different functions of antibodies. Patients diagnosed with thyroid disorders can generate TSH rec.. View More»
DOI:
10.35248/2167-7948.23.12.295