Journal of Thyroid Disorders & Therapy
Open Access

Department of Clinical Laboratory Medicine, Hyogo Medical University School of Medicine, Nishinomiya, Japan

Publications

• Review   
  Autoantibodies as Biomarkers in Thyroid Diseases
  Author(s): Masayoshi Nakano*, Ayako Miyazaki, Hiroe Konishi, Rika Yukimatsu, Toru Watanabe and Masahiro Koshiba
  
  Thyroid diseases are common pathologies in primary care settings, and many patients with such diseases are treated by physicians who are not specialized in thyroid conditions. To diagnose such diseases earlier, some biological biomarkers have been identified. Anti-TSH receptor antibodies, which are considered the cause of Graves’ disease, are autoantibodies that bind to TSH receptors and activate the thyroid gland. The measurement of anti-TSH receptor antibodies is crucial for diagnosing, managing, and monitoring the treatment of Graves’ disease. This test has high sensitivity and specificity as a diagnostic tool. Conversely, antibodies against the TSH receptor do not have just one property; thus, the anti-TSH receptor antibody assay system could be improved to distinguish the different functions of antibodies. Patients diagnosed with thyroid disorders can generate TSH rec.. View More»
  DOI: 10.35248/2167-7948.23.12.295

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