ISSN: 2165-7890
Department of Microbiology, University of Karbala, Karbala, Iraq
Research Article
Role of FOXP1 (SNPS) Gene in Autism Spectrum Disorder Pathogenesis
Author(s): Zainab A Al-Ali, Masar R Al-Mousawi, Ahmed J Al-Karaqully, Alaa S Alattabi, Mohammed Shnain Ali, Liwaa Hussein Mahdi and Falah AM Salih*
Introduction: Autism Spectrum Disorder (ASD) is a group of developmental disorders with multifactorial genetic and environmental etiology. FOXP1 gene product plays an important role in the development of Central Nervous System (CNS) tissues and neuron function. The role of mutations of certain genes as cause of ASD was highly investigated. One of the blamed gene is Single Nucleotide Polymorphism (SNP) of FOXP1 rs112795301 in association with ASD that represents a fruitful area of research.
Aim: To unveil the frequency distribution of FOXP1 SNP rs112795301 and whether it has a role in pathogenesis of ASD patients.
Materials and Methods: A case-control study was done in Faculty of Medicine, University of Kufa from December, 2019 to December, 2020. We determined SNP rs112795301 of F.. View More»
DOI:
10.35248/2165-7890.24.14.397