Journal of Probiotics & Health
Open Access
ISSN: 2329-8901
ISSN: 2329-8901
Department of Microbiology and Virology, Mashhad University of Medical Sciences, Mashhad, Iran
Review Article
Physiological and Immunological Functions and Therapeutic Importance of Probiotics in Allergic Diseases
Author(s): Majid Eslami*, Masoud Keikha, Nazarii M. Kobyliak, Mohsen Karbalaei and Bahman Yousefi
Allergic diseases have been a global problem over the past few decades. The effect of allergic diseases on healthcare systems and society is generally remarkable and is considered as one of the most common causes of chronic and hospitalized disease. The functional ability of probiotics to modulate the innate/acquired immune system leads to the initiation of mucosal/systemic immune responses. Gut microbiota plays a beneficial role in food digestion, development of the immune system, control/growth of the intestinal epithelial cells and their differentiation. Prescribing probiotics causes a significant change in the intestinal microflora and modulate cytokine secretion, including networks of genes, TLRs, signaling molecules and increased intestinal IgA responses. The modulation of Th1/Th2 balance is done by probiotics, which suppresses Th2 responses with shifts to Th1 and thereby preven.. View More»
DOI:
10.35248/2329-8901.24.12.344