ISSN: 2574-0407
+44-77-2385-9429
Mexico
Extended Abstract
Global Toxicology 2020: Food grade titanium dioxide (E171) induces systemic toxicity in mice fed with a high fat diet - Medina-Reyes EI1, UNAM. Mexico
Author(s): Medina Reyes
Food-grade titanium dioxide (E171) is used as additive in food products for human consumption since 1960. Recently, it was demonstrated that intragastric E171 administration enhanced colon tumor formation in experimental models and induced histological alterations in testis. This rises further concerns of E171 as a possible trigger or synergistic diet component of pathologies. Regarding to diet, the increased fat intake jumped 22.8% from 1993 to 2013 worldwide and together with the E171 as a facilitator of colon tumor formation, brings the hypothesis of exacerbated toxicity induced by E171 after oral consumption in mice fed with a high fat diet (HFD). This work aimed to evaluate the toxicity in colon, liver and tes.. View More»