Advanced Techniques in Biology & Medicine
Open Access
ISSN: 2379-1764
ISSN: 2379-1764
Department of Medical Parasitology, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia
Research Article
Role of Secretory Vesicles Derived from Plasmodium Infected Red Blood Cells to the Pathogenesis of Malaria: A Review
Author(s): Awoke Minwuyelet* and Melkam Abiye
Malaria, which is caused by Plasmodium parasites, is one of the most important infectious diseases worldwide. Plasmodium parasites in humans use various pathways to communicate within their own population and to manipulate their outside environments, with the ultimate goal of balancing the rate of growth and transmission. For example, circulating extracellular vesicles are increasingly recognized as the key mediators of physiological and pathological processes of a pathogen. Extracellular vesicles are pathogen products consisting of bi-lipid membrane spheres that are secreted from infected-host cells and contain proteins, lipids, and nucleic acids. Based on size and biogenesis, EVs can be categorized into exosomes (released from multivesicular bodies), microvesicles/microparticles and apoptotic bodies (originated by plasma membrane budding). While the funct.. View More»
DOI:
10.35248/2379-1764.22.10.360