Journal of Women's Health Care
Open Access
ISSN: 2167-0420
ISSN: 2167-0420
Deputy Director for Science, Ural Research Institute of Maternity and Child Care, Russian Ministry of Public Health, Russia
Research
Changes in Tissue Endometrial Receptivity under the Influence of High Intensity Focused Ultrasound during Ablation of Uterine Fibroids in Patients of Reproductive Age
Author(s): Melkozerova Oxana Alexandrovna*, Shchedrina Irina Dmitrievna, Malgina Galina Borisovna, Mikhelson Anna Alekseevna and Chistyakova Guzel Nukhovna
Objective: To investigate the influence of the MRI-guided high-intensity focused ultrasound ablation (HIFU) of uterine fibroids on the endometrial receptivity in patients planning pregnancy.
Material and Methods: A prospective comparative controlled study of 95 reproductive age women planning a pregnancy with symptomatic uterine fibroids was conducted. 32 patients receiving HIFU treatment and 35 women receiving surgical treatment under laparoscopic myomectomy were examined. A control group was existing 28 healthy fertile women, examined voluntarily. The endometrium obtained with pipelle biopsia on days 20-22 of the menstrual cycle was examined by immunohistochemistry before and three months after the treatment. Statistical analysis of the results was carried out using SPSS 22.0.
Results: It was established that the.. View More»
DOI:
10.35248/2167-0420.20.9.491