Journal of Biomedical Engineering and Medical Devices
Open Access
ISSN: 2475-7586
ISSN: 2475-7586
Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, NY, USA
Dr. Michael Gillogly is a Doctor Primarily located in Conroe, TX, with another office in Houston, TX. His specialties include General Dentistry. He was affiliated with University of Texas MD Anderson Cancer Center and other places, His research work- Fine Specificity of High Molecular Weight-Melanoma-Associated Antigen-Specific Cytotoxic T Lymphocytes Elicited by Anti-Idiotypic Monoclonal Antibodies in Patients with Melanoma, Ii-Key/HER-2/ neu MHC class-II antigenic epitope vaccine peptide for breast cancer etc.
Research
Validation of a Novel Noxious Pressure Device for Use in fMRI Pain Studies
Author(s): Marisa DiMarzio, Michael Spinrad, Maria Hancu, Ellinor Grinde, Jamie Chang, Julia Slyer, Michael Gillogly, Julia Prusik, Julie G. Pilitsis*, Eric Fiveland and Ileana Hancu
Background: Most fMRI studies on pain perception utilized thermal stimuli due to the lack of a non-metallic reliable, reproducible mechanical stimulus. We explored 2 potential MR compatible mechanical devices and validated one that induced changes on fMRI.
Purpose: To validate a noxious mechanical stimulus MR compatible device in a healthy cohort and a chronic pain cohort. Further to ensure this device caused changes on fMRI compared to a pressure device.
Methods: Two-healthy controls underwent fMRI scans in the presence/absence of mechanical noxious stimuli using different devices. A paradigm for administering the stimuli with the most robust responses on fMRI was developed. Reproducibility of the device was confirmed in 10 chronic pain patients and age/gender-matched healthy controls. Comparisons of patient demog.. View More»
DOI:
10.35248/2475-7586.19.4.138