ISSN: 2736-6588
Department of Immunology, Orleans University, Orleans, France
Short Communication
Cytotoxicity Assessment of Sea- Star Protein SIP-Young-6His in MCF-7 Cells
Author(s): Michel Leclerc*
The objective of this project is to assess whether recombinant protein SIP-Young-6His, produced in HEK293, induces
cell death in MCF-7 cells. To achieve this, the metabolic activity is measured with the Cell Cytotoxicity Assay Kit
(Abnova, Ref# KA4151) which contains a water-soluble dye that changes its absorption spectra upon cellular
reduction. In first analysis it seems that sea star protein SIP-Young-6His have a weak cytotoxicity against MCF7 cells
when compared to Doxorubicin activity against these same tumoral cells... View More»
DOI:
10.35248/ JCCLM.22.5.224