Medical & Surgical Urology
Open Access

Department of Urology and Andrology, Grand Yoff General Hospital, Dakar, Senegal

Publications

• Mini Review   
  Treatment of Muscle Invasive Urothelial Bladder Cancer- A Review of the Literature
  Author(s): Ayun Cassell*, Bashir Yunusa, Mouhamadou M. Mbodji, Mohamed Jalloh, Abdourahmane Diallo, Yoro Diallo, Issa Labou, Lamine Niang and Serigne M. Gueye
  
  Carcinoma of the bladder is the fourth and fifth most frequently diagnosed cancer in the United States and Europe respectively. Muscle-Invasive Urothelial Bladder Cancer (MIBC) (cT2-T4) is an aggressive disease with poor 5-year Overall Survival (OS) of 50%. Epidemiological studies are unavailable in most African countries; however, Africa was found to have a lower incidence. Current optimal management is based on Radical Cystectomy (RC) and pelvic Lymph Node Dissection (LND), generally associated with pre-operative cisplatin-based chemotherapy. Adjuvant chemotherapy may be necessary in patients who did not benefit from neoadjuvant chemotherapy. A selected few patients who desire bladder preservation may benefit from bladder sparing procedures but should be cautioned about the risk of recurrence. The African literature lacks structured prospective studies on the management of urothelia.. View More»
  DOI: 10.35248/2168-9857.19.8.223

  Abstract HTML PDF