Journal of Molecular Pathology and Biochemistry
Open Access
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Department of Neurophysiology, KOC University, Istanbul, Turkey
Research Article
Auditory and Visual Mating Cues Input, Interaction among the Central Biological clock and Reproductive Neuron in Hypothalamic-Pituitary-Gonadal Axis of Rhesus Monkey: A Potential Cause of Precocious Puberty
Author(s): Muhammad Aslam*
Hypothalamic Pituitary Gonadal Axis (HPG) operates and gated by multiple neuro-circuits one of which is circadian
system. Circadian system is necessary for reproduction. The impact of day, night length, electromagnetic radiation,
hormone and food on circadian cycle and onset of puberty was well established but influence of two crucial visual
and auditory mating cues was not yet determined. Biological clock Suprachiasmatic Nucleus (SCN) is connected to
other reproduction regulating areas such as Preoptic Area (POA) Antero-Ventral Periventricular Nucleus (AVPV)
Arcuate Nucleus (ARC) and Dorsomedial Hypothalamus (DMH). Our finding has proved exposure of Visual and
auditory mating cues significantly increased circadian clock regulatory protein expression GnRH neuropeptide and
neurohormone that impart confounding impact on reproductive organ growth and early onset of p.. View More»
DOI:
10.35248/ JMPB.23.4.152