Internal Medicine: Open Access
Open Access

Department of Diabetes and Endocrinology, Hull University Teaching Hospitals, Hull, United Kingdom

Biography

Doctor Najeeb Shah works in the Department of Diabetes and Endocrinology, Hull University Teaching Hospitals, Hull, United Kingdom in field of Public Health. One of his renowned works is Langerhans Cell Histiocytosis Presenting with Central Diabetes Insipidus in an Adult: A Case Report with a Discussion on Differential Diagnosis, Diagnostic Workup and Treatment.

Publications

• Case Report   
  Langerhans Cell Histiocytosis Presenting with Central Diabetes Insipidus in an Adult: A Case Report with a Discussion on Differential Diagnosis, Diagnostic Work up and Treatment
  Author(s): Najeeb Shah*, Harshal Deshmukh, Shiva Mongolu, Muhammad Jawaid Akbar, Shah Rukh Malik, Shahbaz Nazir and Somil Rastogi
  
  Langerhans Cell Histiocytosis (LCH) is rare in adults; the condition affects 1-2 patients per million annually in the general population. Diabetes Insipidus (DI) is a common manifestation of Langerhans Cell Histiocytosis (LCH) although its reported frequency varies in different series. The pathogenesis of the condition is not precisely understood. Infiltration of the hypothalamic-pituitary axis by Langerhans-like cells has been reported in 50% of autopsied patients. Central Diabetes Insipidus (CDI) can be familial, idiopathic or secondary and is a disorder characterised by polyuria, polydipsia and formation of hypotonic urine... View More»
  DOI: 10.35248/2165-8048.21.11.333

  Abstract HTML PDF