Journal of Applied Pharmacy
Open Access
ISSN: 1920-4159
+44 1300 500008
ISSN: 1920-4159
+44 1300 500008
Department of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717, USA
He is a recipient of many awards and grants for his valuable contributions and discoveries in major area of subject research. His international experience includes various programs, contributions and participation in different countries for diverse fields of study. Her research interests reflect in her wide range of publications in various national and international journals which includes Aerobic bacterial methane synthesis, Electronic Cigarette Refill Liquids: Nicotine Content, Presence of Child-Resistant Packaging, and in-Shop Compounding.
Research Article
Metabolic Profiling of Eclipta prostrata L.: Potentials of Untargeted Metabolomics in Traditional Medicine
Author(s): Jesse M. Thomas and Narayanaganesh Balasubramanian*
We have demonstrated the use of untargeted metabolomics- a high-throughput analysis to probe the small molecule landscape of natural products based traditional medicine. The approach provides a global perspective on the quality of such natural medicine and the depth of secondary metabolites present in them. We utilized Eclipta prostrata L. as an example to demonstrate the utility of LC-MS and GC-MS based untargeted metabolomics. The mentioned research utilized three different preparations and successfully demonstrated the small molecule landscape differences in these samples. Preliminary statistical analysis using R-based web programs, indicated the samples grouped well indicating batch-to-batch consistency. Heatmaps generated from LC-MS and GC-MS data indicated the difference in abundance of various small molecules across the samples... View More»