Journal of Pharmacological Reports
Open Access

Department of Chemical Science, Spiritan University, Nneochi, Nigeria

Publications

• Research Article   
  Changes in Serum Electrolyte Balance in Menopausal Women Administered with Anxiolytes
  Author(s): Anikwe Uchenna, Chukwudozie Izuchukwu Christopher, Chibuike K Uwakwe, Okenwa Ezinne Jennifer and Oparaji Emeka H*
  
  The present study is designed to monitor the anxiolytic effects of diazepam (benzodiazepines) and its association with changes of serum electrolyte balance among forty (40) selected women within menopausal cycle. The experiment was carried out for four weeks and drug administrations were done orally. Serum electrolyte (sodium (Na+), potassium (K +), chloride ion (Cl-) and Bicarbonate (CO3) concentrations (mg/ml) experimented in the reproductive women showed differential changes in all the tested women orally administered with diazepams when compared with the control experiment (women not administered with the anxiolytic drug) during the four weeks of experiment. Na+ and K+ showed a concentration of 144 mg/ml and 4.1 mg/ml after seven days (week 1) of administrations and progressively decreases to 142.5 mg/ml and 4.1 mg/.. View More»
  DOI: 10.35248/JPR.22.6.129

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