ISSN: 2167-0420
Department of Pathology, Faculty of Medicine, Zagazig University, Zagazig, Egypt
Ola A Harb, affiliated with Department of Pathology, Faculty of Medicine, Zagazig University, Zagazig, Egypt He have 82 publications on online global platform. His specialization and research interest includes Cancer, Cell Biology, Tumours, Diagnosis, Metastasis, Tumour Biology.
Review
Vitamin D Supplemental Therapy can Explore the Interplay Circuit between Hypovitaminosis D, High Serum IL-6 and Pregnancy-Associated Morbidities
Author(s): Khaled Fathy Helal* and Ola A Harb
Objectives: To evaluate the relation between baseline Vitamin D (VD) serum levels and incidence and severity of Pregnancy-Associated Morbidities (PAM).
Patients and methods: The study included 386 pregnant women attended at the 6th gestational week and after full clinical and obstetric examination, gave fasting blood samples for estimation of fasting blood glucose (FBG) and ELISA estimation of serum VD, insulin and interleukin-6 (IL-6). Insulin resistance (IR) was determined according to homeostasis model assessment IR (HOMA-IR) score that was considered abnormal at score of ≥ 2. Enrolled women were categorized according to a booking VD level as sufficient (Group A), insufficient (Group B) and deficient (Group C). Women of group C received daily oral VD (1000 IU) supplemental therapy (VD-ST) till delivery. Study outcomes included incidenc.. View More»