Journal of Clinical and Experimental Ophthalmology
Open Access

Department of Ophthalmology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic

Publications

• Research Article   
  Optimizing Vision Restoration: Experience with Holoclar Treatment, the Selection of a Qualified Treatment Center, Accessibility to Patients and Outcomes
  Author(s): Cecilia Marinova*, Eva Vlkova, Monika Horackova, Magdalena Netukova, Pavlina Skalicka, Graziella Pellegrini, Veronika Sladkova, Martina Losova and Sandra Skvarlova
  
  Moving towards personalized medicine brings the novel challenge of connecting highly specific treatments with the patients who can benefit from them. One such treatment is the cell therapy Holoclar®, approved for use in adult patients with moderate to severe Limbal Stem Cell Deficiency (LSCD) caused by trauma (burns, chemical burns to the eyes). It takes significant effort and time to establish a qualified Holoclar® Treatment Center (HTC). The efficacy of an HTC is assessed based upon the number of treated patients. We evaluated new approaches to improving patient access to the HTC and thus commercial sustainability for Holoclar®. We mapped new patient pathways and the role of cooperation, networking, coordination among centers and clinical outcomes and focused on the accessibility of Holoclar® acros.. View More»
  DOI: 10.35248/2155-9570.24.15.971

  Abstract HTML PDF