Journal of Cancer Research and Immuno-Oncology
Open Access

Department of Neuro-Oncology, Sheba Medical Center, Ramat Gan, Israel

Publications

• Research Article   
  Prediction of Local Failure for Post-Operative Radiotherapy of Resected Brain Metastases in Breast Cancer Patients
  Author(s): Jie Feng*, Glassner Saechs, Rachel Patel, Piang Liang and Nicolas Guieu
  
  Single brain metastasis surgical resection remains an effective treatment for brain metastases. However, surgery alone associate with a high rate of local failure. The current guidelines recommend radiation to surgical cavity. The recommended dose for brain cavity after surgery remain to be define as most guidelines gives a very general suggestion about the dose and fractionation. The aim of this study was to determine what variable influence local control in this specific population. Methods Retrospective analysis of 52 patients with breast cancer who undergo surgical resection to single brain metastases and who received post-operative radiotherapy between the years 2010- 2022. All clinical and dosimetric variables were analyzed to evaluate their impact on local control. A predictive model for local control was calculated. Results One year local control was 65.3.. View More»
  DOI: 10.35248/2684-1266.23.09.197

  Abstract HTML PDF