Journal of Clinical & Experimental Dermatology Research
Open Access

Department of Medical, Surgical and Neurological Sciences, Dermatology Unit, University Hospital of Siena, Siena, Italy

Publications

• Research Article   
  Prevention Strategies in Patients affected by Actinic Keratosis of the Head: A 12-Month, Prospective, Assessor-Blinded, Controlled Study with Lesion-Directed Treatment Associated with Medicalized Photoprotection
  Author(s): Arianna Lamberti, Alessandra Cartocci, Carolina Donelli, Giulio Cortonesi, Emanuele Trovato, Massimo Milani*, Pietro Rubegni and Elisa Cinotti
  
  Objective: We assessed the efficacy of a 100+SPF sunscreen containing DNA-repairing enzymes (endonuclease, glycosylase, and photolyase) and a potent antioxidant extract (Polypodium Leucotomos Extract: PLE) (“Medicalized” Photoprotection: MP), in subjects with Actinic Keratosis (AK) treated with cryotherapy measuring the evolution of AKASI score and through a non-invasive analysis with Line-field Confocal-Optical Coherence Tomography (LC)- OCT. Patients and Methods: A prospective, 12-month, assessor-blinded, controlled study enrolling patients with ≤ 5 actinic keratoses on the face and/or scalp suitable for cryotherapy was performed. After cryotherapy, 30 subjects were instructed to apply the MP twice daily for 12 consecutive months. Thirty subjects were selected as a control group. AKASI score was evaluated .. View More»
  DOI: 10.35841/2329-9509.22.13.620

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