Journal of Clinical Trials
Open Access
ISSN: 2167-0870
ISSN: 2167-0870
Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es salaam, Tanzania
Research Article
Correlates and Short-Term Prognostic Value of Plasma N-Terminal Pro- Brain Natriuretic Peptide Levels among Heart Failure Patients; in a Wake
of COVID-19 Pandemic: A Prospective Cohort Study
Author(s): Mark. P. Mayala*, Khuzeima Khanbhai, Ponsian Peter and Pilly Chillo
Background: Studies conducted in developed countries have found measurements of plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) to be important in evaluating Heart Failure (HF) prognosis; however this has not yet been studied in sub-Saharan Africa. The aim of this study was to determine clinical correlates and short-term prognostic value of plasma NT-proBNP levels among HF patients.
Methodology: This was a hospital-based prospective cohort study conducted at Jakaya Kikwete Cardiac Institute, Tanzania from June to December 2020. Patients were consecutively enrolled when they fulfilled the inclusion criteria. Clinical details and NT-proBNP levels were measured at baseline and at 30-day follow-up. Pearson's chi square test was used to associate New York Heart Association (NYHA) functional class and NT-proBNP levels, while Spearm.. View More»