Journal of Clinical & Experimental Dermatology Research
Open Access

Lecturer, Faculty of Medicine, Department of Dermatology and Venerology, Beni Suef University, Egypt

Biography

Dr. Rehab Mohamed Naguib Department of Dermatology and Venerology, Beni Suef University, Port Saed Street, Beni Suef, Egypt. Dr. has a Special interest in Dermatology, Venereology, Pediatrics, Medical Doctor, pathology.

Publications

• Research Article   
  Expression of Long Non-coding RNA in Psoriasis
  Author(s): Abd-El Aziz El-Rifaie, Rehab Mohamed Naguib*, Laila Ahmed Rashed and Esraa Mohamed Rasheed
  
  Background: Psoriasis is a chronic hyper proliferative inflammatory disease, in which genetic and environmental factors have an important role, but the exact cause is yet unknown. Long non coding RNA (lncRNAs) act as a key regulator for the inflammatory gene expression by collaborating with the transcription factors. Aim: Detection of the expression of long non coding RNA in psoriatic skin of diseased patients as compared to normal control persons to investigate the possible role of long non coding RNA in the psoriasis pathogenesis Subjects and methods: The present study included 30 psoriatic patients and 30 age, gender-matched healthy controls. 4 mm punch skin biopsy was taken from patients (psoriatic lesion) & control and it was kept in lysis solution for the stability of the studied parameters and was kept frozen at -80°C till analysis of long non coding RNA by qRT PCR. Res.. View More»
  

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