Journal of Clinical Chemistry and Laboratory Medicine
Open Access

Department of Biochemistry and Biotechnology, Kenyatta University, Nairobi, Kenya

Publications

• Short Communication   
  The Significance of NanoVelcro Chip in Cancer Detection
  Author(s): Richard Meon Gitimu*
  
  Photo Circulating tumor cells (CTC) are cells that are circulating in the blood which are shred either from primary tumor site in benign state or metastatic region. The NanoVelcro CTC Chip, a device made out of a patterned silicon nanowire substrate (SiNS) and an overlaid polydimethylsiloxane (PDMS) blender. There are four generations of NanoVelcro CTC tests created over the previous decade for an assortment of clinical utilities. The first gen NanoVelcro chips, made from silicon nanowire substrate (SiNS) and microfluidic blender, and were made for identification of CTC. The second gen NanoVelcro chips (i.e., NanoVelcro-LMD), in light of polymer nanosubstrates, were produced for single-CTC isolation which is related to the utilization of the laser microdissection (LMD) procedure. By grafting thermoresponsive polymer brushes onto SiNS, the third generation thermore.. View More»
  DOI: 10.35248/jcclm.21.4.185

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